Publications

2008
Hellmann, I., Mang, Y., Gu, Z., Li, P., de la Vega, F.M., Clark, A.G., Nielsen, R. Population genetic analysis of shotgun assemblies of genomic sequences from multiple
individuals. (in press) Genome Res. DATA

2007
Nielsen, R., Hellmann, I., Hubisz, M., Bustamante, C., Clark, A.G. (2007) Recent and ongoing selection in the human genome. Nat. Rev. Genet. 8: 857-68.

Weber, M., Hellmann, I., Stadler, M.B., Ramos, L., Pääbo, S., Rebhan, M. ,Schübeler, D. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome.  Nat. Genet. 39: 457-66.

2006
Khaitovich, P., Tang, K., Franz, H., Kelso, J., Hellmann, I., Enard, W., Lachmann, M., Paabo, S. (2006) Positive selection on gene expression in the human brain. Curr. Biol. 16: R365-8.
2005 Hellmann, I., Prüfer, K., Ji, H., Zody, M.C., Paabo, S. and Ptak, S.E. (2005) Why do human diversity levels vary at a megabase scale? Genome Res.15: 1222-31. Khaitovich, P.°, Hellmann, I.°, Enard, W.°, Nowick, K., Leinweber, M., Franz, H., Weiss, G., Lachmann, M. and Paabo, S. (2005) Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees. Science. 309: 1850-4. Mikkelsen, T.S., Hillier, L.W., Eichler, E.E., Zody, M.C., Jaffe, D.B., Yang, S.-P., Enard, W., Hellmann, I., Lindblad-Toh, K., Altheide, T.K., Archidiacono, N., Bork, P., Butler, J., Chang, J.L., Cheng, Z., Chinwalla, A.T., deJong, P., Delehaunty, K.D., Fronick, C.C., Fulton, L.L., Gilad, Y., Glusman, G., Gnerre, S., Graves, T.A., T., H., Hayden, K.E., Huang, X., Ji, H., Kent, W.J., King, M.-C., Kulbokas III, E.J., Lee, M.K., Liu, G., Lopez-Otin, C., Makova, K.D., Man, O., Mardis, E.R., Mauceli, E., Miner, T.L., Nash, W.E., Nelson, J.O., Pääbo, S., Patterson, N.J., Pohl, C.S., Pollard, K.S., Prüfer, K., Puente, X.S., Reich, D., Rocchi, M., Rosenbloom, K., Ruvolo, M., Richter, D.J., Schaffner, S.F., Smit, A.F.A., Smith, S.M., Suyama, M., Taylor, J., Torrents, D., Tuzun, E., Varki, A., Velasco, G., Ventura, M., Wallis, J.W., Wendl, M.C., Wilson, R.K., Lander, E.S. and Waterston, R.H. (2005) Initial sequence of the chimpanzee genome and comparison with the human genome. Nature. 437: 69-87.

2004 Watanabe, H., Fujiyama, A., Hattori, M., Taylor, T.D., Toyoda, A., Kuroki, Y., Noguchi, H., BenKahla, A., Lehrach, H., Sudbrak, R., Kube, M., Taenzer, S., Galgoczy, P., Platzer, M., Scharfe, M., Nordsiek, G., Blocker, H., Hellmann, I., Khaitovich, P., Paabo, S., Reinhardt, R., Zheng, H.J., Zhang, X.L., Zhu, G.F., Wang, B.F., Fu, G., Ren, S.X., Zhao, G.P., Chen, Z., Lee, Y.S., Cheong, J.E., Choi, S.H., Wu, K.M., Liu, T.T., Hsiao, K.J., Tsai, S.F., Kim, C.G., S, O.O., Kitano, T., Kohara, Y., Saitou, N., Park, H.S., Wang, S.Y., Yaspo, M.L. and Sakaki, Y. (2004) DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature. 429: 382-388. Khaitovich, P., Weiss, G., Lachmann, M., Hellmann, I., Enard, W., Muetzel, B., Wirkner, U., Ansorge, W. and Paabo, S. (2004) A neutral model of transcriptome evolution. PLoS Biol. 2: E132. Khaitovich, P., Muetzel, B., She, X., Lachmann, M., Hellmann, I., Dietzsch, J., Steigele, S., Do, H.H., Weiss, G., Enard, W., Heissig, F., Arendt, T., Nieselt-Struwe, K., Eichler, E.E. and Paabo, S. (2004) Regional patterns of gene expression in human and chimpanzee brains. Genome Res. 14: 1462-1473.
2003 Hellmann, I., Zollner, S., Enard, W., Ebersberger, I., Nickel, B. and Paabo, S. (2003) Selection on human genes as revealed by comparisons to chimpanzee cDNA. Genome Res. 13: 831-837. Hellmann, I., Ebersberger, I., Ptak, S.E., Paabo, S. and Przeworski, M. (2003) A neutral explanation for the correlation of diversity with recombination rates in humans. Am J Hum Genet. 72: 1527-1535.
° these authors contributed