About

I am a postdoc with Anders Krogh at the Bioinformatics Center, University of Copenhagen.

My background is a B.Sc. degree in mathematics and computer science, a M.Sc. degree in Bioinformatics and a Ph.D. degree in Bioinformatics.

Research interests

My research interests include:

• Probabilistic methods in structural biology
• Graphical models and dynamic Bayesian networks
• Markov chain Monte Carlo methods
• Directional statistics

Education

Publications

Peer-reviewed

• Olsson S, Boomsma W, Frellsen J, Bottaro S, Harder T, Ferkinghoff-Borg J, Hamelryck T (2011) Generative probabilistic models extend the scope of inferential structure determination. J Magn Reson 213(1):182-186. doi:10.1016/j.jmr.2011.08.039
• Hamelryck T, Borg M, Paluszewski M, Paulsen, Frellsen J, Andreetta C, Boomsma W, Bottaro S, Ferkinghoff-Borg J (2010) Potentials of Mean Force for Protein Structure Prediction Vindicated, Formalized and Generalized. PLoS ONE 5:e13714. doi:10.1371/journal.pone.0013714
• Harder T, Boomsma W, Paluszewski M, Frellsen J, Johansson KE, Hamelryck T (2010) Beyond rotamers: a generative, probabilistic model of side chains in proteins. BMC Bioinformatics 11:306. doi:10.1186/1471-2105-11-306
• Frellsen J, Moltke I, Thiim M, Mardia KV, Ferkinghoff-Borg J, Hamelryck T (2009) A Probabilistic Model of RNA Conformational Space. PLoS Comput Biol 5(6): e1000406. doi:10.1371/journal.pcbi.1000406
• Marstrand TT, Frellsen J, Moltke I, Thiim M, Valen E, Retelska D, Krogh A (2008) Asap: A Framework for Over-Representation Statistics for Transcription Factor Binding Sites. PLoS ONE 3(2): e1623. doi:10.1371/journal.pone.0001623

Non-peer-reviewed

• Borg M, Mardia KV, Boomsma W, Frellsen J, Harder T, Stovgaard K, Ferkinghoff-Borg J, Røgen P, Hamelryck T (2009) A probabilistic approach to protein structure prediction: PHAISTOS in CASP9. LASR2009 - Statistical tools for challenges in bioinformatics pp 65-70. Leeds, Leeds University Press.
• Boomsma W, Borg M, Frellsen J, Harder T, Stovgaard K, Ferkinghoff-Borg J, Krogh A, Mardia KV and Hamelryck, T (2008) PHAISTOS: protein structure prediction using a probabilistic model of local structure. Proceedings of CASP8 pp 82-83.

Presentations (talks)

• Internal Seminar, Fred Hutchinson Cancer Research Center, USA, May 2010.
• Computational methods for RNA analysis, Centro de Ciencias de Benaque Pedro Pascual, Spain, July 2009.
• The 27th Leeds Annual Statistical Research Workshop (LASR 2008), University of Leeds, July 2008.
• Statistics Seminars, University of Leeds, April 2008.
• IMA Workshop: RNA in Biology, Bioengineering and Nanotechnology, University of Minnesota, October 2007.

Software

Teaching

Lecturer

I have been lecturing parts of the following classes at The Bioinformatics Center, University of Copenhagen:

• Introduction to Bioinformatics - Spring 2009, Spring 2010, Spring 2011
• Structural Bioinformatics - Fall 2007, Fall 2008, Fall 2009

Assistant

I have been a teaching assistant at the Institute for Mathematical Sciences, University of Copenhagen, and at the Department of Mathematics and Physics, The Royal Veterinary and Agricultural University. I have been a teaching assistant in the following classes:

• Numerical Solution of Ordinary Differential Equations - Fall 2005, Fall 2006
• Introduction to numerical methods - Spring 2006
• Model (Mathematical Modeling) - Fall 2005
• LaTeX (LaTeX-Course) - Fall 2005, Fall 2006
• Databehandling (Computer science for students of the veterinary and agricultural sciences) - Spring 2004
• Datalogi A (Computer science for mathematicians) - Fall 2001, Fall 2002 and Fall 2003

Contact Information